A case of hepatitis C virus-associated mixed cryoglobulinemic vasculitis treated with daclatasvir and asunaprevir
نویسندگان
چکیده
منابع مشابه
Daclatasvir/asunaprevir based direct-acting antiviral therapy ameliorate hepatitis C virus-associated cryoglobulinemic membranoproliferative glomerulonephritis: a case report
BACKGROUND Direct-acting antivirals (DAAs) dramatically improve the treatment of hepatitis C virus (HCV) infections. However, the effects of DAAs on extra-hepatic manifestations such as HCV-associated glomerulonephritis, especially in cases with renal dysfunction, are not well elucidated. CASE PRESENTATION A 69-year-old Japanese woman was diagnosed as having chronic hepatitis C, genotype 1b a...
متن کاملA Rare Case of Hepatitis C-Associated Cryoglobulinemic Duodenal Vasculitis
Intestinal involvement of cryoglobulinemia is an uncommon manifestation and marker of severe vasculitis. We describe the case of a woman admitted to our service for management of acute renal failure and progressive gastrointestinal symptoms after initiating hepatitis C virus treatment with ribavirin and sofosbuvir 4 weeks prior. With an undetectable hepatitis C viral load and persistent symptom...
متن کاملComplex Pattern of Resistance-Associated Substitutions of Hepatitis C Virus after Daclatasvir/Asunaprevir Treatment Failure
BACKGROUNDS & AIMS We aimed to clarify the characteristics of resistance-associated substitutions (RASs) after treatment failure with NS5A inhibitor, daclatasvir (DCV) in combination with NS3/4A inhibitor, asunaprevir (ASV), in patients with chronic hepatitis C virus genotype 1b infection. METHODS This is a nationwide multicenter study conducted by the Japanese Red Cross Liver Study Group. Th...
متن کاملTherapy for hepatitis C virus-related cryoglobulinemic vasculitis.
Copyright © 2013 Massachusetts Medical Society. Cryoglobulins are immunoglobulins characterized by their insolubility at low temperatures and their dissolution after rewarming.1,2 On the basis of their immunochemical composition, cryoglobulins are classified as either single (type I), consisting of a monoclonal immunoglobulin, or mixed, comprising two or more immunoglobulin isotypes, with (type...
متن کاملSafety and efficacy of daclatasvir and asunaprevir in hepatitis C virus-infected patients with renal impairment.
AIM Hepatitis C virus (HCV) infection is a risk factor for end-stage renal disease, renal graft failure, and hemodialysis patient mortality. However, the efficacy of direct-acting antiviral therapy for HCV-infected patients with renal impairment is unclear. Additionally, the promising NS5B inhibitor sofosbuvir has not been recommended for patients with severe renal impairment. In this prospecti...
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ژورنال
عنوان ژورنال: Kanzo
سال: 2016
ISSN: 0451-4203,1881-3593
DOI: 10.2957/kanzo.57.328